Primary Identifier | MGI:2444314 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 270120 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable calcium ion binding activity. Acts upstream of or within generation of neurons; negative regulation of dendrite development; and retina layer formation. Located in dendrite. Is expressed in several structures, including brain; foregut; ganglia; sensory organ; and skeleton. Orthologous to human FAT3 (FAT atypical cadherin 3). PHENOTYPE: Mice homozgyous for a knock-out allele exhibit abnormal amacrine cell differentiation and migration that result in the formation of two additional plexiform layers and thickened retinal ganglion layer. [provided by MGI curators] |