Primary Identifier | MGI:2158460 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 234988 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methyl-CpG binding activity. Predicted to be involved in DNA methylation-dependent constitutive heterochromatin formation and negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Orthologous to several human genes including MBD3L2 (methyl-CpG binding domain protein 3 like 2); MBD3L2B (methyl-CpG binding domain protein 3 like 2B); and MBD3L3 (methyl-CpG binding domain protein 3 like 3). PHENOTYPE: Homozygous null mice are viable and fertile. [provided by MGI curators] |