Primary Identifier | MGI:109157 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 15571 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables mRNA 3'-UTR AU-rich region binding activity. Predicted to be involved in cell differentiation and nervous system development. Predicted to be part of ribonucleoprotein complex. Is expressed in several structures, including central nervous system; enteric nervous system; eye; intestine; and primitive bladder. Orthologous to human ELAVL3 (ELAV like RNA binding protein 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit strain-specific preweaning lethality, abnormal cortical hypersynchronization and non-convulsive electropgraphic seizure. Mice heterozygous for the allele exhibit abnormal brain wave pattern and spike wave discharge. [provided by MGI curators] |