Primary Identifier | MGI:2143362 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235047 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sequence-specific DNA binding activity. Acts upstream of or within innate immune response and negative regulation of single stranded viral RNA replication via double stranded DNA intermediate. Located in nucleus. Is expressed in several structures, including central nervous system; early conceptus; and genitourinary system. PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased expression of VL30-pro endogenous retroviruses (ERV) elements. [provided by MGI curators] |