Primary Identifier | MGI:1335094 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 235072 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activity; identical protein binding activity; and molecular adaptor activity. Predicted to be a structural constituent of postsynapse. Acts upstream of or within several processes, including D-glucose import; cortical cytoskeleton organization; and plasma membrane bounded cell projection organization. Located in axon terminus; neuronal cell body; and septin cytoskeleton. Part of septin complex. Is active in cytoplasm; presynaptic membrane; and vesicle. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SEPTIN7 (septin 7). PHENOTYPE: Mice homozygous for a conditional allele activated in neurons exhibit reduced axon and dendrite length and complexity. Mice homozygous for a knock-out allele die prior to E10.5. [provided by MGI curators] |