| Primary Identifier | MGI:2142989 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 78658 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methylated histone binding activity. Involved in positive regulation of chromosome segregation and positive regulation of chromosome separation. Acts upstream of or within meiotic chromosome separation. Located in condensed nuclear chromosome; germinal vesicle; and kinetochore. Part of condensin complex. Is expressed in cerebral cortex subventricular zone. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human NCAPD3 (non-SMC condensin II complex subunit D3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality between implantation and somite formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
