Primary Identifier | MGI:2450166 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 330914 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTPase activator activity. Predicted to be involved in positive regulation of axon extension; positive regulation of neuron migration; and small GTPase-mediated signal transduction. Predicted to act upstream of or within Rho protein signal transduction. Located in actin cytoskeleton; cell cortex; and postsynaptic density. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Used to study autism spectrum disorder. Orthologous to human ARHGAP32 (Rho GTPase activating protein 32). PHENOTYPE: Mice homozygous for a null mutation are fertile but display abnormal neurite growth. [provided by MGI curators] |