| Primary Identifier | MGI:95554 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 14247 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including blood circulation; megakaryocyte development; and regulation of DNA-templated transcription. Located in nucleus. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study systemic scleroderma. Human ortholog(s) of this gene implicated in blood platelet disease and thrombocytopenia. Orthologous to human FLI1 (Fli-1 proto-oncogene, ETS transcription factor). PHENOTYPE: Mice homozygous for most knock-out allele exhibit abnormal hematopoietic and immune systems. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
