Primary Identifier | MGI:1914953 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 67703 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cell adhesion molecule binding activity. Involved in hemopoiesis; homophilic cell adhesion via plasma membrane adhesion molecules; and nervous system development. Acts upstream of or within glomerulus morphogenesis; inter-male aggressive behavior; and nervous system development. Located in several cellular components, including axon; dendritic shaft; and extracellular region. Is expressed in several structures, including Rathke's pouch; branchial arch; central nervous system; limb bud; and sensory organ. Orthologous to human KIRREL3 (kirre like nephrin family adhesion molecule 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired accessory olfactory bulb formation with reduced coalescence of vomeronasal sensory neuron axons in the posterior accessory olfactory bulb, loss of male-male aggression and abnormal male sexual response to a male intruder mouse. [provided by MGI curators] |