Primary Identifier | MGI:1929693 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 56857 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable glucose 6-phosphate:phosphate antiporter activity and glycerol-3-phosphate transmembrane transporter activity. Predicted to be involved in glucose-6-phosphate transport and phosphate ion transmembrane transport. Predicted to act upstream of or within glycerol-3-phosphate metabolic process; glycerol-3-phosphate transmembrane transport; and glycerophosphate shuttle. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human SLC37A2 (solute carrier family 37 member 2). PHENOTYPE: Mice homozygous for a null allele exhibit increased pro-inflammatory cytokine production and accelerated glycolysis and mitochondrial oxidation in macrophages. [provided by MGI curators] |