| Primary Identifier | MGI:1927184 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 64011 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calmodulin binding activity. Predicted to be involved in positive regulation of long-term synaptic potentiation and postsynaptic modulation of chemical synaptic transmission. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in several cellular components, including dendritic spine head; neuronal cell body; and trans-Golgi network transport vesicle membrane. Predicted to be active in glutamatergic synapse and postsynaptic membrane. Is expressed in several structures, including brain; genitourinary system; hemolymphoid system gland; liver; and stomach. Orthologous to human NRGN (neurogranin). PHENOTYPE: Homozygotes for a targeted null mutation exhibit impaired spatial learning and altered hippocampal short- and long-term plasticity. Heterozygotes show milder effects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
