Primary Identifier | MGI:1100877 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 21376 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in several processes, including DNA replication; protein localization to nucleoplasm; and protein stabilization. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including cranium; genitourinary system; jaw; liver; and spleen. Orthologous to human TBRG1 (transforming growth factor beta regulator 1). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit increased embryonic survival and increased tumor incidence including B cell lymphoma. [provided by MGI curators] |