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Protein Coding Gene : Panx3 pannexin 3
Primary Identifier  MGI:1918881 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  208098
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables calcium channel activity and gap junction hemi-channel activity. Involved in osteoblast differentiation. Located in endoplasmic reticulum membrane; gap junction; and plasma membrane. Is expressed in several structures, including alimentary system; connective tissue; limb; sensory organ; and skeleton. Orthologous to human PANX3 (pannexin 3).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit protection against surgically induced osteoarthritis. [provided by MGI curators]
  • synonyms:
  • pannexin 3,
  • Panx3,
  • 4833413G11Rik,
  • RIKEN cDNA 4833413G11 gene
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