| Primary Identifier | MGI:1922917 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 75667 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables protein phosphatase 1 binding activity and protein phosphatase inhibitor activity. Involved in negative regulation of phosphatase activity. Located in inner acrosomal membrane and outer acrosomal membrane. Orthologous to human TMEM225 (transmembrane protein 225). PHENOTYPE: Male mice homozygous for a knock-out allele are infertile and exhibit asthenospermia and an abnormal hairpin-loop configuration in cauda sperm flagella associated with impaired glycolysis, decreased ATP levels, high reactive oxygen species levels, and mitochondrial dysfunction. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
