Primary Identifier | MGI:2669849 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 244813 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within eating behavior; locomotory behavior; and mammary gland involution. Located in nucleus. Part of transcription regulator complex. Is expressed in brain; metanephros; and renal vasculature. Orthologous to human BSX (brain specific homeobox). PHENOTYPE: Mice homozygous for mutations in Bsx display increased fat mass, decreased food intake after fasting, decreased body temperature, and reduced locomotor activity, but body weight and glucose homoeostasis are similar to wild-type. [provided by MGI curators] |