Primary Identifier | MGI:2429611 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 270151 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP binding activity. Acts upstream of or within negative regulation of canonical NF-kappaB signal transduction; negative regulation of cytokine production; and regulation of defense response. Located in mitochondrion. Is expressed in cerebral cortex ventricular layer and cortical plate. Orthologous to human NLRX1 (NLR family member X1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to viral infection. [provided by MGI curators] |