Primary Identifier | MGI:1890594 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 192663 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables ABC-type sterol transporter activity. Involved in several processes, including cholesterol efflux; cholesterol homeostasis; and positive regulation of cholesterol biosynthetic process. Acts upstream of or within cellular response to leukemia inhibitory factor. Located in endosome membrane. Is expressed in several structures, including genitourinary system; immune system; liver; nervous system; and sensory organ. Orthologous to human ABCG4 (ATP binding cassette subfamily G member 4). PHENOTYPE: Mice homozygous for a report allele exhibit increased brain lathosterol levels. [provided by MGI curators] |