| Primary Identifier | MGI:102688 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 15270 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables damaged DNA binding activity. Acts upstream of or within double-strand break repair via homologous recombination and spermatogenesis. Located in chromosome and male germ cell nucleus. Is expressed in several structures, including central nervous system; early conceptus; eye; gonad; and heart. Orthologous to human H2AX (H2A.X variant histone). PHENOTYPE: Homozygous null mice are smaller and display increased susceptibility to ionizing radiation, male infertility, T and B cell abnormalities, and increased genomic instability. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
