| Primary Identifier | MGI:2682935 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 214531 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase activity. Acts upstream of or within establishment of skin barrier. Predicted to be located in cytoplasm; extracellular region; and plasma membrane. Is expressed in several structures, including alimentary system; eye; genitourinary system; heart; and immune system. Orthologous to human TMPRSS13 (transmembrane serine protease 13). PHENOTYPE: Mice homozygous for a knock-out allele are viable and outwardly healthy but exhibit abnormal stratum corneum formation leading to impaired skin barrier function, as measured by the transepidermal fluid loss rate in newborn pups. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
