| Primary Identifier | MGI:1913363 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 66113 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including cholesterol transfer activity; enzyme activator activity; and heparin binding activity. Involved in acylglycerol homeostasis. Acts upstream of or within triglyceride metabolic process and triglyceride-rich lipoprotein particle remodeling. Predicted to be located in extracellular space. Predicted to be part of chylomicron; high-density lipoprotein particle; and very-low-density lipoprotein particle. Predicted to be active in extracellular vesicle. Is expressed in lung. Human ortholog(s) of this gene implicated in cerebral infarction; coronary artery disease; familial hyperlipidemia (multiple); and type 2 diabetes mellitus. Orthologous to human APOA5 (apolipoprotein A5). PHENOTYPE: Homozygous mutation of this gene results in increased triglyceride and VLDL cholesterol levels. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
