| Primary Identifier | MGI:2177469 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 170752 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables beta,beta-carotene-9',10'-cleaving oxygenase activity. Involved in isoprenoid catabolic process; regulation of mitochondrial membrane potential; and regulation of reactive oxygen species metabolic process. Acts upstream of or within retinal metabolic process and xanthophyll metabolic process. Located in mitochondrion. Is expressed in brain; embryo; liver; placenta; and yolk sac. Orthologous to human BCO2 (beta-carotene oxygenase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased spleen weight, decreased testis and seminal vesicle weight, and increased tissue lycopene and beta-carotene levels when fed diets containing tomato powder or lycopene. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
