| Primary Identifier | MGI:1098246 | Organism | mouse, laboratory |
| Chromosome | 18 | NCBI Gene Number | 100042150 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Enables receptor ligand activity. Involved in ERBB2-ERBB3 signaling pathway and ERBB4-ERBB4 signaling pathway. Is active in extracellular region. Is expressed in several structures, including epidermis; heart; main olfactory bulb layer; mammary gland primordium; and surface ectoderm. Orthologous to human NRG2 (neuregulin 2). PHENOTYPE: About one third of mice homozygous for a knock-out allele die prior to weaning in the absence of cardiac defects or other morphological abnormalities. Homozygotes display an early but transient postnatal growth deficit and reduced reproductive capacity. [provided by MGI curators] |