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Protein Coding Gene : Hspb2 heat shock protein 2

Primary Identifier  MGI:1916503 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  69253
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable unfolded protein binding activity. Acts upstream of or within somatic muscle development. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including adrenal gland; cardiovascular system; gut; limb segment; and skeletal musculature. Orthologous to human HSPB2 (heat shock protein family B (small) member 2).
PHENOTYPE: Mice homozygous for a conditional allele activated in the heart exhibit reduced state 3 mitochondrial respiration and ATP production following transverse aortic constriction despite normal cardiac hypertrophic response. [provided by MGI curators]
  • synonyms:
  • MKBP,
  • heat shock protein 2,
  • RIKEN cDNA 2810021G24 gene,
  • HSP27,
  • Hspb2,
  • 27kDa,
  • 2810021G24Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For