Primary Identifier | MGI:1916503 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 69253 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable unfolded protein binding activity. Acts upstream of or within somatic muscle development. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including adrenal gland; cardiovascular system; gut; limb segment; and skeletal musculature. Orthologous to human HSPB2 (heat shock protein family B (small) member 2). PHENOTYPE: Mice homozygous for a conditional allele activated in the heart exhibit reduced state 3 mitochondrial respiration and ATP production following transverse aortic constriction despite normal cardiac hypertrophic response. [provided by MGI curators] |