| Primary Identifier | MGI:1920949 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 73699 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein phosphatase regulator activity. Predicted to be involved in several processes, including meiotic sister chromatid cohesion, centromeric; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; and spindle assembly. Is active in glutamatergic synapse. Is expressed in several structures, including cerebral cortex; eye; genitourinary system; thymus primordium; and tooth. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human PPP2R1B (protein phosphatase 2 scaffold subunit Abeta). PHENOTYPE: Homozygous null males are infertile, exhibit non-obstructive azoospermia, impaired meiotic recombination and arrest of male meiosis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
