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Protein Coding Gene : Btg4 BTG anti-proliferation factor 4

Primary Identifier  MGI:1860140 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  56057
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables mRNA 3'-UTR binding activity. Acts upstream of or within maternal-to-zygotic transition of gene expression and negative regulation of mitotic cell cycle. Predicted to be located in cytosol. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system; early embryo; gonad; nasal cavity epithelium; and retina. Orthologous to human BTG4 (BTG anti-proliferation factor 4).
PHENOTYPE: Female mice homozygous for mutations in this gene produce morphologically normal oocytes but exhibit defects during maternal-zygotic transition and are infertile because embryos arrest after fertilization at the 1- or 2-cell stage. [provided by MGI curators]
  • synonyms:
  • PC3B,
  • BTG anti-proliferation factor 4,
  • expressed sequence C86116,
  • Btg4,
  • MGI:2143430,
  • C86116

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For