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Protein Coding Gene : Npat nuclear protein in the AT region
Primary Identifier  MGI:107605 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  244879
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable transcription coactivator activity and transcription corepressor activity. Acts upstream of or within in utero embryonic development. Predicted to be located in Cajal body; Gemini of coiled bodies; and cytoplasm. Predicted to be active in nucleus. Is expressed in inner cell mass. Orthologous to human NPAT (nuclear protein, coactivator of histone transcription).
PHENOTYPE: Homozygous null embryos fail to proceed from the morula to blastocyst stage and have an uncompacted appearance. [provided by MGI curators]
  • synonyms:
  • expressed sequence BB112559,
  • BB112559,
  • expressed sequence AI427561,
  • AI427561,
  • MGI:2143040,
  • nuclear protein in the AT region,
  • Npat,
  • MGD-MRK-36179,
  • MGI:2143360
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