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Protein Coding Gene : Sln sarcolipin

Primary Identifier  MGI:1913652 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  66402
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable enzyme regulator activity. Involved in several processes, including positive regulation of cold-induced thermogenesis; regulation of ATPase-coupled calcium transmembrane transporter activity; and sarcoplasmic reticulum calcium ion transport. Acts upstream of or within negative regulation of ATPase-coupled calcium transmembrane transporter activity. Located in sarcoplasmic reticulum membrane. Is expressed in several structures, including diaphragm; embryo mesenchyme; heart atrium; musculature; and tongue. Orthologous to human SLN (sarcolipin).
PHENOTYPE: Mice homozygous for a null allele exhibit increased cardiac contractility and impaired muscle-based thermogenesis. [provided by MGI curators]
  • synonyms:
  • 2310045A07Rik,
  • sarcolipin,
  • Sln,
  • RIKEN cDNA 2310045A07 gene

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

1 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For