| Primary Identifier | MGI:109156 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 104360 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within negative regulation of neuron differentiation and neuron differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; genitourinary system; peripheral nervous system; and retina. Orthologous to human ISL2 (ISL LIM homeobox 2). PHENOTYPE: Mutations of this gene result in neonatal lethality, motor neuron migration defects and impaired visceral motor neuron differentiation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
