| Primary Identifier | MGI:1321396 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 19200 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin binding activity and protein phosphatase binding activity. Predicted to be involved in several processes, including endocytosis; inflammatory response; and innate immune response. Located in actomyosin contractile ring; cleavage furrow; and stress fiber. Is expressed in several structures, including genitourinary system; liver; musculature; pancreas; and spleen. Human ortholog(s) of this gene implicated in PAPA syndrome. Orthologous to human PSTPIP1 (proline-serine-threonine phosphatase interacting protein 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit defects in immune cells with T cell hyperresponsive to antigen receptor stimulation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
