Primary Identifier | MGI:2442366 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 244895 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity and non-membrane spanning protein tyrosine kinase activity. Predicted to be involved in several processes, including focal adhesion assembly; regulation of focal adhesion assembly; and substrate adhesion-dependent cell spreading. Located in actin cytoskeleton and focal adhesion. Orthologous to human PEAK1 (pseudopodium enriched atypical kinase 1). PHENOTYPE: Mice homozygous for a null allele exhibit reduced angiogenesis in postnatal retina, VEGFA-treated aortas, and transplanted breast cancer cells infected with VEGFA-expressing adenovirus. [provided by MGI curators] |