| Primary Identifier | MGI:1915522 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 235402 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables epidermal growth factor receptor binding activity. Acts upstream of or within negative regulation of oligodendrocyte differentiation; negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction; and neuron development. Is active in glutamatergic synapse and presynapse. Is expressed in several structures, including branchial arch; central nervous system; gut; sensory organ; and somite. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 64 and glaucoma. Orthologous to human LINGO1 (leucine rich repeat and Ig domain containing 1). PHENOTYPE: Mice homozygous for a knock-out allele exhibit early-onset CNS myelination. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
