| Primary Identifier | MGI:1928376 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 56294 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in signal transduction. Predicted to act upstream of or within negative regulation of neuron projection development; peptidyl-tyrosine dephosphorylation; and positive regulation of protein localization to plasma membrane. Located in neuron projection terminus. Is expressed in several structures, including brain; genitourinary system; liver; lung; and spleen. Orthologous to human PTPN9 (protein tyrosine phosphatase non-receptor type 9). PHENOTYPE: Mice homozygous for a null allele display hemorrhages, craniofacial anomalies, neural tube defects such as exencephaly and meningomyeloceles, cerebral infarctions, abnormal bone development, and >90% late embryonic lethality in addition to severe defectsin T lymphocyte and platelet activation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
