Primary Identifier | MGI:1349645 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 26968 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Located in extracellular space. Is expressed in several structures, including embryo mesenchyme; genitourinary system; gut gland; meninges; and retina layer. Orthologous to human ISLR (immunoglobulin superfamily containing leucine rich repeat). PHENOTYPE: The gene product suppresses differentiation of bone marrow stromal and skeletal stem cells into skeletal lineages. Homozygous knockout leads to growth retardation and longer long bones. [provided by MGI curators] |