| Primary Identifier | MGI:1921536 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 74286 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin binding activity. Involved in sperm axoneme assembly and sperm mitochondrial sheath assembly. Located in acrosomal vesicle and sperm midpiece. Orthologous to human TBC1D21 (TBC1 domain family member 21). PHENOTYPE: Homozygous inactivation of this gene causes male infertility associated with abnormal sperm flagellum morphology. Mice homozygous for a knock-out allele exhibit decreased sperm progressive motility and sperm tail defects including mitochondrial and axonemal abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
