Primary Identifier | MGI:1097159 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 18007 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables BMP receptor binding activity; cadherin binding activity; and signaling receptor activity. Involved in trans-synaptic signaling, modulating synaptic transmission. Acts upstream of or within several processes, including myoblast fusion; negative regulation of axon regeneration; and positive regulation of BMP signaling pathway. Located in several cellular components, including cell surface; growth cone; and intracellular vesicle. Is active in glutamatergic synapse and postsynaptic density membrane. Is expressed in several structures, including alimentary system; genitourinary system; limb; nervous system; and sensory organ. Orthologous to human NEO1 (neogenin 1). PHENOTYPE: Mice homozygous for a gene trap allele display perinatal lethality and abnormal trigeminal nerve development. [provided by MGI curators] |