| Primary Identifier | MGI:1919815 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 72565 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables transcription regulator inhibitor activity. Involved in negative regulation of canonical NF-kappaB signal transduction and negative regulation of non-canonical NF-kappaB signal transduction. Acts upstream of or within several processes, including intrinsic apoptotic signaling pathway; positive regulation of cysteine-type endopeptidase activity; and positive regulation of protein import into nucleus. Located in several cellular components, including cytosol; nuclear envelope; and perinuclear region of cytoplasm. Part of apoptosome. Is expressed in several structures, including cerebral cortex ventricular layer; genitourinary system; heart; liver; and lung. Used to study hepatocellular carcinoma. Orthologous to human UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats). PHENOTYPE: Homozygous mice display swelling of and inflammatory lesions in the preputial gland. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
