Primary Identifier | MGI:104634 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 21887 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Involved in negative regulation of cold-induced thermogenesis. Predicted to be located in nucleoplasm. Predicted to be part of beta-catenin-TCF complex. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human TLE3 (TLE family member 3, transcriptional corepressor). PHENOTYPE: Mice homzoygous for a gene trap allele exhibit embryonic lethality. [provided by MGI curators] |