| Primary Identifier | MGI:2444283 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 235431 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity; talin binding activity; and vinculin binding activity. Acts upstream of or within focal adhesion assembly; negative regulation of stress fiber assembly; and regulation of glomerular filtration. Located in focal adhesion. Is expressed in cerebral cortex; dorsal root ganglion; and hippocampus. Orthologous to human CORO2B (coronin 2B). PHENOTYPE: Homozygous knockout reduces susceptibility to Doxorubicin-induced focal segmental glomerulosclerosis with lower levels of proteinuria and less renal glomerulus damage. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
