Primary Identifier | MGI:1858202 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 53869 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including G protein activity; GTP binding activity; and cytoskeletal protein binding activity. Involved in melanosome transport. Acts upstream of or within protein localization to cell surface and protein transmembrane transport. Located in centriole; membrane; and recycling endosome. Is expressed in several structures, including adrenal gland; early conceptus; esophagus; eye; and genitourinary system. Orthologous to human RAB11A (RAB11A, member RAS oncogene family). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators] |