| Primary Identifier | MGI:1916856 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 69606 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable methionyl-tRNA formyltransferase activity. Predicted to be involved in conversion of methionyl-tRNA to N-formyl-methionyl-tRNA. Located in mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 15 and nuclear type mitochondrial complex I deficiency 27. Orthologous to human MTFMT (mitochondrial methionyl-tRNA formyltransferase). PHENOTYPE: Mice homozygous for a null allele display embryonic lethality with mitochondrial abnormalities. Male mice heterozygous for a null mutation display resistance to high-fat diet induced metabolic changes. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
