Primary Identifier | MGI:2143132 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 102595 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within macrophage apoptotic process. Orthologous to human PLEKHO2 (pleckstrin homology domain containing O2). PHENOTYPE: Mice homozygous for a null allele exhibit reduced macrophages in the spleen, blood and peritoneal cavity due to increased apoptosis. [provided by MGI curators] |