Primary Identifier | MGI:1915276 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 68026 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable chromatin binding activity and molecular adaptor activity. Predicted to be involved in several processes, including DNA metabolic process; centrosome cycle; and response to UV. Predicted to be located in centrosome and perinuclear region of cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; facial prominence; limb; and skin. Orthologous to human PCLAF (PCNA clamp associated factor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit impaired hematopoietic stem cell function and development. [provided by MGI curators] |