Primary Identifier | MGI:1928395 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 56440 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable phosphatidylinositol binding activity; protein dimerization activity; and signaling receptor binding activity. Involved in neuron projection development. Acts upstream of or within negative regulation of transforming growth factor beta receptor signaling pathway. Located in several cellular components, including dendritic spine; early endosome; and postsynaptic density. Is active in postsynaptic density, intracellular component. Is extrinsic component of postsynaptic endosome membrane. Is expressed in several structures, including egg cylinder and small intestine. Orthologous to human SNX1 (sorting nexin 1). PHENOTYPE: Homozygous mutant mice are viable and fertile and do not exhibit any apparent abnormalities. [provided by MGI curators] |