Primary Identifier | MGI:1915191 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 67941 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA binding activity; cysteine-type endopeptidase activator activity involved in apoptotic process; and translation activator activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in intracellular signal transduction; positive regulation of protein metabolic process; and ribosomal small subunit assembly. Predicted to be located in nucleus. Predicted to be part of cytosolic small ribosomal subunit. Is expressed in several structures, including alimentary system; lung; nose; skeletal musculature; and ventricular layer. Orthologous to human RPS27L (ribosomal protein S27 like). PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete postnatal lethality, decreased body weight, hypoplasia of the thymus cortex and liver, and decreased HSC numbers and function. [provided by MGI curators] |