Primary Identifier | MGI:1927549 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 64290 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sequence-specific DNA binding activity. Involved in several processes, including mammary gland development; nervous system development; and visual learning. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; jaw; limb; and paraxial mesenchyme. Orthologous to human FOXB1 (forkhead box B1). PHENOTYPE: Targeted null mutant mice show variable embryonic lethality with neural tube defects or severe posterior reduction. Survivors have high postnatal mortality, reduced growth, motor weakness, midbrain abnormalities and females have a lactational defect. [provided by MGI curators] |