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Protein Coding Gene : Foxb1 forkhead box B1

Primary Identifier  MGI:1927549 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  64290
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables sequence-specific DNA binding activity. Involved in several processes, including mammary gland development; nervous system development; and visual learning. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; jaw; limb; and paraxial mesenchyme. Orthologous to human FOXB1 (forkhead box B1).
PHENOTYPE: Targeted null mutant mice show variable embryonic lethality with neural tube defects or severe posterior reduction. Survivors have high postnatal mortality, reduced growth, motor weakness, midbrain abnormalities and females have a lactational defect. [provided by MGI curators]
  • synonyms:
  • MGI:103153,
  • Foxb1a,
  • forkhead homolog 5, (Drosophila),
  • forkhead box B1,
  • Mf3,
  • TWH,
  • mesoderm/mesenchyme forkhead 3,
  • Fkh5,
  • MGI:1347486,
  • MGD-MRK-39569,
  • MGD-MRK-9817,
  • MGI:109570,
  • Foxb1,
  • Hfh-e5.1,
  • MGD-MRK-24019,
  • forkhead box B1a,
  • Foxb1b,
  • MGI:95548,
  • C43,
  • forkhead box B1b

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

1 Driver For