Primary Identifier | MGI:103032 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 20255 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within protein localization to secretory granule. Located in secretory granule membrane. Is expressed in several structures, including adrenal gland; alimentary system; genitourinary system; nervous system; and sensory organ. Orthologous to human SCG3 (secretogranin III). PHENOTYPE: Homozygous knockout causes dysregulation of the secretion of active peptide hormones from endocrine cells, exacerbating the adverse effects of inadequate diet (obesity, diabetes) and stress conditions. [provided by MGI curators] |