| Primary Identifier | MGI:88181 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 12160 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable BMP receptor binding activity and cytokine activity. Involved in several processes, including allantois development; chordate embryonic development; and heart development. Acts upstream of or within several processes, including anterior head development; ear development; and male genitalia development. Predicted to be located in vesicle. Predicted to be active in extracellular space. Is expressed in several structures, including bone; central nervous system; embryo mesenchyme; limb; and sensory organ. Used to study Meier-Gorlin syndrome. Orthologous to human BMP5 (bone morphogenetic protein 5). PHENOTYPE: Homozygous recessive mutants have shortened, slightly ruffled external ears due to a defective cartilage framework affecting the whole skeleton; a series of genomic deletions of the region cause embryonic lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
