Primary Identifier | MGI:1915218 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 67968 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Involved in several processes, including cytoskeleton organization; positive regulation of double-strand break repair via homologous recombination; and positive regulation of meiotic nuclear division. Acts upstream of or within several processes, including embryo implantation; establishment or maintenance of apical/basal cell polarity; and protein phosphorylation. Located in apical part of cell; cell cortex; and nucleus. Part of subcortical maternal complex. Is expressed in several structures, including early conceptus; nervous system; nose; ovary; and skeleton. Orthologous to human OOEP (oocyte expressed protein). PHENOTYPE: Mice homozygous for a null allele exhibit female infertility associated with a failure of embryos to progress beyond the 2 cell stage. [provided by MGI curators] |