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Protein Coding Gene : Hmgn3 high mobility group nucleosomal binding domain 3

Primary Identifier  MGI:2138069 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  94353
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables chromatin binding activity. Acts upstream of or within positive regulation of DNA-binding transcription factor activity; positive regulation of transcription by RNA polymerase II; and regulation of insulin secretion involved in cellular response to glucose stimulus. Located in nucleus. Is expressed in several structures, including central nervous system; epithelium; eye; genitourinary system; and limb. Orthologous to human HMGN3 (high mobility group nucleosomal binding domain 3).
PHENOTYPE: Mice homozygous for a null allele exhibit impaired glucose tolerance with decreased insulin serum levels and increased glucose serum levels during feeding. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 6330514M13 gene,
  • 6330514M13Rik,
  • TRIP7,
  • HMGN3a,
  • 1110002A15Rik,
  • expressed sequence BB071015,
  • Hmgn3,
  • MGI:1914636,
  • MGI:2143355,
  • RIKEN cDNA 1110002A15 gene,
  • high mobility group nucleosomal binding domain 3,
  • MGI:1923404,
  • BB071015,
  • HMGN3b

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

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1 Involved In Mutations

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0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For